Uninstalled Game leaves AppData can I delete?

Hi,

I'm trying to clean up some files and disk space... I've uninstalled a few games but they are leaving behind folders and files in the various user/AppData area.
Examples Germany at War leaves folders in Appdata/local Legions of Steel leaves Folders in Appdata Local low Train Fever is leaving a big file in Appdata Roaming multiple folders (363 MB) seams to be a map cache. Any ideas ... can I delete this stuff?
Please help.

I didn't find the right solution from the Internet.

References:
www.matrixgames.com/forums/tm.asp?m=4362351
Electronic Product Marketing


Thanks